Webb1 sep. 2024 · In the Prospective Randomized On-X Valve Anticoagulation Clinical Trial (PROACT), patients with at least 1 thromboembolic risk factor were randomized to standard warfarin therapy (INR goal 2.0-3.0) or lower-dose warfarin (INR goal 1.5-2.0). 21 Major bleeding events were significantly less likely in the lower-INR arm (1.48% vs … WebbThe most common reason patients were withdrawn from the low-risk arm prior to randomization and moved to the high-risk arm of the PROACT trial was inadequate …
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Webb20 juli 2024 · Objective: The objectives of this study are to design and develop a digital health platform, ProACT, for facilitating older adults self-managing multimorbidity, with support from their care network, and evaluate end user engagement and experiences with this platform through a 12-month trial. Methods: The ProACT digital health platform is ... Webb29 sep. 2024 · September 29, 2024 Artivion Inc. has halted the PROACT Xa clinical trial that was testing whether patients with an On-X mechanical aortic valve could be safely … funnel chart template powerpoint free
Longer-Term Outcomes of the ProACT Trial - nejm.org
Webb31 mars 2024 · The Prospective Randomized On-X Valve Anticoagulation Clinical Trial (PROACT) was designed to compare standard versus low anticoagulation targets in high … WebbRising antimicrobial resistance rates represent an alarming threat to public health, currently causing over 25 000 and 23 000 deaths per year in European Union and the USA, respectively [1, 2]. The significant global overuse of antibiotics amplifies the development of resistant bacterial strains [1, 2]. A recent national audit in the USA estimated that … Webb1 jan. 2011 · Principal Findings: A total of 861 patients were enrolled in the trial; this preliminary report outlines results for 435 high-risk AVR patients. Of these, 185 patients … funnel chemistry drawing