Kif1c anthrax
WebAnthrax toxin is the dominant virulence factor of Bacillus anthracis and drugs blocking its action could therefore have therapeutic benefit. Three recent papers suggest new ways to inhibit the toxin. Identification of the cell surface toxin receptor could lead to the design of binding competitors and receptor decoys. Determination of the crystal structure of the … WebAbout KIF1C Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:4,997,950-5,028,401 (from NCBI) This gene has 4 transcripts (splice variants), 186 orthologues, 41 paralogues and is associated with 2 phenotypes. Ubiquitous expression in heart (RPKM 51.8), fat (RPKM 28.5) and 24 other tissues. Summary
Kif1c anthrax
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WebAnthrax is a severe bacterial infection that occurs when Bacillus anthracis spores gain access into the body and germinate in macrophages, ... Finally, protection from LT might …
Web1. Introduction. The three toxin polypeptides encoded by the Bacillus anthracis pXO1 plasmid combine in binary combinations to form two toxins, lethal toxin (LT) and edema … WebThis suggested that the sensitivity to LT in the originally established Kif1c knockout mice was not due to the loss of the Kif1c gene, but was because of the presence of the …
Web1 okt. 2001 · At first glance, Kif1C appeared an unlikely protagonist. Anthrax launches its attack in the body by releasing a deadly toxin which has a remarkable mechanism for … Web1 okt. 2001 · Kif1C, a kinesin-like motor protein, mediates mouse macrophage resistance to anthrax lethal factor. Coronavirus: Find the latest articles and preprints Sign in or create …
WebTyrosine phosphorylation is a putative regulator of KIF1C mediated retrograde transport of Golgi vesicles to the endoplasmic reticulum. KIF1C is capable of forming homodimers …
Web2 okt. 2001 · In October Current Biology, James Watters and colleagues from Harvard Medical School, Boston, show that Kif1C, a kinesin-like motor protein, is responsible for … bucksaw fishing report truman lakeWeb29 mrt. 2010 · Background In Bacillus anthracis, lethal toxin (LeTx) is a critical virulence factor that causes immune suppression and toxic shock in the infected host. NF-κB is a … bucksaw leather journalWebResults and Discussion The BMP-4 precursor undergoes ordered cleavage at two sites within the prodomain. Our previous studies on proteolytic activation of BMP-4 suggested that proBMP-4 may be cleaved at more than one site within the prodomain (Cui et al. 1998).To test this possibility, [35 S]proBMP-4 was incubated with 5 nm of recombinant furin in vitro … buck sawhorseWebWe offer KIF1C Antibodies for use in common research applications: ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot. Each KIF1C Antibody is fully covered by our Guarantee+, to give you complete peace of mind and the support when you need it. cree hensonWebDOI: 10.1016/S0960-9822(01)00476-6 Corpus ID: 16408765; Kif1C, a kinesin-like motor protein, mediates mouse macrophage resistance to anthrax lethal factor … bucksaw products coWeb13 nov. 2001 · A new study has found that polymorphisms in the host gene kif1C, which encodes a kinesin-like motor protein, determine whether mouse macrophages are … bucksaw point campgroundWebAnthrax toxin is the dominant virulence factor of Bacillus anthracis and drugs blocking its action could therefore have therapeutic benefit. Three recent papers suggest new ways … bucksaw marina campground