WebIntravesical Hydrogels as Drug Reservoirs. Article. Jan 2024; Heping Qiu. Hui Guo. Di Li [...] Jianxun Ding. The complex environment in the bladder weakens the efficacy of intravesical therapy. WebEncouragingly, the development of injectable hydrogels for the treatment of OP has attracted increasing attention in recent years because they can serve either as a …
Current status of the development of intravesical drug delivery systems ...
WebRecent advances in intravesical drug delivery are to use hydrogels as drug reservoir to extend the drug residence time in bladder. However, because of the high viscosity of hydrogel, urinary obstruction is usually existed during the intravesical instillation. To overcome these, we developed a floating hydrogel for the delivery of Adriamycin (ADR). WebJun 1, 2024 · Hydrogels can provide spatial and temporal control over the release of various therapeutic agents, including small-molecule drugs, macromolecular drugs and cells. david sowell facebook
Synthesis, classification and properties of hydrogels: their ...
WebThe complex environment in the bladder weakens the efficacy of intravesical therapy. Hydrogel-based drug delivery systems are poised to revolutionize the delivery of therapeutic agents to bladder lesion sites. This forum article highlights the prospective applications of hydrogels as drug reservoirs in treating chronic bladder diseases. WebA floating hydrogel delivery system was developed using perfluoropentane (PFP) as the floating agent, which addresses the problems of conventional intravesical instillation and is promising for clinic use. Abstract Intravesical drug delivery is the main strategy for the treatment of bladder disorders. To reduce the relief arising from frequent intravesical … WebOct 22, 2024 · Hydrogels are high water-retainable materials with a three-dimensional (3D) polymeric network ... Kuang T, Ding J. Intravesical hydrogels as drug reservoirs. Trends Biotechnol. (2024) 38:579–83. 10.1016/j.tibtech.2024.12.012 [Google Scholar] 18. Klouda L. Thermoresponsive hydrogels in biomedical applications: a seven-year ... gastric bypass north carolina